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Eating too many calories, eating the wrong kinds of carbohydrate foods, and lack of physical activity put people with metabolic syndromes muscle might or risk for obesity and type 2 diabetes, but even before those problem appear, frequent spiking of blood sugar will favor glycation and its long-term detrimental effects on healthy. It may be that half the population or more has this genetic heritage. And even those without it would do well to learn the difference between quickly digested and slowly digested carbohydrates, because eating fewer of the former and more of the latter is better for optimum health. The quickly digested ones are often low-quality foods that should not be prominent in a diet for healthy aging.